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Mestinonpyridostigmine bromideis a drug commonly used for treating myasthenia gravisThe drug is currently under investigation for spinal muscular atrophySMA
Pyridostigmine is used to improve muscle strength in patients with a certain muscle diseasemyasthenia gravisIt works by preventing the breakdown of a certain natural substanceacetylcholinein your bodyAcetylcholine is needed for normal muscle function.
The side effects of Mestinonpyridostigmineare most commonly related to overdosage and generally are of two varietiesmuscarinic and nicotinicAmong those in the former group are nauseavomitingdiarrheaabdominal crampsincreased peristalsisincreased salivationincreased bronchial secretionsmiosis and diaphoresisNicotinic side effects are comprised chiefly of muscle crampsfasciculation and weaknessMuscarinic side effects can usually be counteracted by atropinebut for reasons shown in the preceding section the expedient is not without dangerAs with any compound containing the bromide radicala skin rash may be seen in an occasional patientSuch reactions usually subside promptly upon discontinuance of the medication.
Take this medication by mouth with or without food as directed by your doctorIf you are using the liquid form of this medicationcarefully measure the dose using a special measuring device/spoonDo not use a household spoon because you may not get the correct dose.
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